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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REEP4 All Species: 20.3
Human Site: T204 Identified Species: 40.61
UniProt: Q9H6H4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6H4 NP_079508.2 257 29395 T204 E D E C W S D T E A V P R A P
Chimpanzee Pan troglodytes XP_001153858 257 29395 T204 E D E C W S D T E A V P R A P
Rhesus Macaque Macaca mulatta XP_001102353 257 29523 T204 E D E C W S D T E A V P R A P
Dog Lupus familis XP_543255 413 45887 T360 E D E C W S D T E A V P Q P P
Cat Felis silvestris
Mouse Mus musculus Q8K072 257 29672 N204 E D E C W S D N E I V P Q P P
Rat Rattus norvegicus Q4QQW1 257 29642 N204 E D E C W S D N E I A P Q P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508033 254 28447 S201 E E E C W S D S E V S S Q P P
Chicken Gallus gallus XP_421536 431 48387 E380 G D D R T D E E V E G T H S E
Frog Xenopus laevis NP_001086898 261 29803 E204 D E R W S D S E I A E T R T A
Zebra Danio Brachydanio rerio Q4KMI4 268 30092 S204 D T E S Q H S S R S D D Q S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10010 229 26592 S180 I E E L D E N S D T D L Q K S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GXE9 258 29531 W206 Q T S R G R K W P P P T P P P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.2 57.3 N.A. 88.3 88.7 N.A. 74.3 32.2 64.7 50 N.A. N.A. N.A. 37.3 N.A.
Protein Similarity: 100 100 98.4 58.5 N.A. 91 91.8 N.A. 82 41 77.3 67.5 N.A. N.A. N.A. 57.2 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 73.3 66.6 N.A. 53.3 6.6 13.3 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 80 73.3 N.A. 73.3 26.6 26.6 40 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 42 9 0 0 25 9 % A
% Cys: 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 59 9 0 9 17 59 0 9 0 17 9 0 0 9 % D
% Glu: 59 25 75 0 0 9 9 17 59 9 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 9 17 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % K
% Leu: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 17 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 9 9 50 9 42 67 % P
% Gln: 9 0 0 0 9 0 0 0 0 0 0 0 50 0 0 % Q
% Arg: 0 0 9 17 0 9 0 0 9 0 0 0 34 0 0 % R
% Ser: 0 0 9 9 9 59 17 25 0 9 9 9 0 17 9 % S
% Thr: 0 17 0 0 9 0 0 34 0 9 0 25 0 9 0 % T
% Val: 0 0 0 0 0 0 0 0 9 9 42 0 0 0 0 % V
% Trp: 0 0 0 9 59 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _